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Experts from Brigham Young University in Utah found out that addiction is a result of an 'overcorrection' inside brain, a PsychCentral report said.

Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err to the side of caution and let the FDA do its job and demand some investigation be done so the public knows the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on his or her medications.

Researchers found out that participants taking this drug to get a year, dropped a few pounds within a month and have kept the load off through the 56 weeks with the study. Contrave can be a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of multiple active ingredient, which can make them more potent and safer.

Combo-pilling may be the newest fad or also the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that at the time of right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure level and heartbeat, and really should not be used in people who have a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure levels and heartrate and must not be used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.


"This could be the first drug I'm mindful of that targets the two appetite and reward centres inside the brain," he was quoted saying.